LYMPHOID NEOPLASIA Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma
نویسندگان
چکیده
1Division of Oncology, Center for Applied Medical Research, University of Navarra, Pamplona, Spain; 2Department of Genetics, University of Navarra, Pamplona, Spain; 3 Hematology & Cell Therapy Programs, Clinica Universidad de Navarra, Pamplona, Spain; 4Department of Nuclear Medicine, Clinica Universidad de Navarra, Pamplona, Spain; 5Department of Hematology, Hospital Universitario and Center of Cancer Research, University of Salamanca-CSIC, Salamanca, Spain; and 6Department of Hematology, Reina Sofia Hospital, Maimonides Institute for Biomedical Research, Cordoba, Spain
منابع مشابه
Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma.
In Burkitt lymphoma/leukemia (BL), achievement of complete remission with first-line chemotherapy remains a challenging issue, as most patients who respond remain disease-free, whereas those refractory have few options of being rescued with salvage therapies. The mechanisms underlying BL chemoresistance and how it can be circumvented remain undetermined. We previously reported the frequent inac...
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